Peer Review Study Links Archives - Page 11 of 16

Mechanical properties and cytotoxicity of experimental soft lining materials based on urethane acrylate oligomers

The purpose of this investigation was to determine whether experimental light-curing soft lining materials (ESLMs) based on commercially available urethane acrylate oligomers (UA-160TM, UV-3200B, UV-3500BA, and UV-3700B) are suitable for clinical use by measuring their viscosity, compressive modulus, Shore A hardness, tensile strength, adhesive strength, and cytotoxicity. The viscosities of the four ESLMs at 25 ... Read more

Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts

OBJECTIVES: Aim of this study was by continuous monitoring to assay the proliferative capacity of human gingival fibroblasts (HGFs), to investigate cytotoxicity of the most common monomers/comonomers in dental resin composites: bisphenol-A-glycidylmethacrylate (BisGMA), hydroxyethylenemethacrylate (HEMA), triethyleneglycoldimethacrylate (TEGDMA), and urethanedimethacrylate (UDMA) in HGFs during 24h exposure using the xCELLigence system. SIGNIFICANCE: Our data suggests that the ... Read more

Induction of DNA double-strand breaks in primary gingival fibroblasts by exposure to dental resin composites

Dental resin composites and their reactive monomers/co-monomers have been shown to elicit cytotoxic responses in human gingival fibroblasts (HGF), and their metabolic radical intermediates have the potential to attack the DNA backbone, which may induce DNA double-strand breaks (DSBs). In this study we have tested the cytotoxicity and induction of DSBs by the most common ... Read more

Effect of microwave postpolymerization treatment and of storage time in water on the cytotoxicity of denture base and reline acrylic resins

Microwave irradiation may be considered an alternative to reduce the cytotoxicity of Tokuyama Rebase II. Dental practitioners should choose Lucitone 550 processed with terminal boiling stage.

Cytotoxicity of Titanium and Titanium Alloying Elements

It is commonly accepted that titanium and the titanium alloying elements of tantalum, niobium, zirconium, molybdenum, tin, and silicon are biocompatible. However, research in the development of new titanium alloys for biomedical applications indicated that some titanium alloys containing molybdenum, niobium, and silicon produced by powder metallurgy show a certain degree of cytotoxicity. This group ... Read more

Ongoing Study: Dose-dependent Anti-inflammatory Effects of Vitamin D3 in a Human Gingivitis Model

Dietary vitamin D supplementation may be a simple, safe and inexpensive means by which to reduce gingivitis, as well as to reduce overall oral disease. The burden of chronic gingivitis and periodontitis in the US is disproportionately high among Non-Hispanic Blacks compared to Non-Hispanic Whites. Data from in-vitro and animal studies suggest anti-inflammatory effects of ... Read more

Invasive Dental Treatment and Risk for Vascular Events

When performing dental treatments for patients with vascular disease, providers may wish to warn patients that vascular events increase in the first 4 weeks after invasive dental treatment. Treatment of periodontal disease may reduce cardiovascular risk in the longer term, but studies have suggested a link among dental procedures, acute inflammation, and endothelial dysfunction. However, ... Read more

Fatty Acid Profiles in Smokers with Chronic Periodontitis

Smoking is associated with specific structural alterations to the lipid-A-derived 3-OH fatty acid profile in saliva that are consistent with an oral microflora of reduced inflammatory potential. These findings provide much-needed mechanistic insight into the established clinical conundrum of increased infection with periodontal pathogens but reduced clinical inflammation in smokers.

Oxidative Stress, Systemic Inflammation, and Severe Periodontitis

Periodontal infections have been associated with a state of chronic inflammation. To ascertain whether severe periodontitis and its treatment are associated with oxidative stress, we recruited 145 cases (periodontitis) and 56 controls in a case-control study. A further pilot intervention study of 14 cases (periodontal therapy) was performed. Blood samples were taken at baseline (case-control) ... Read more

Supplementation of green tea catechins in dentifrices suppresses gingival oxidative stress and periodontal inflammation

Adding green tea catechins to a dentifrice may contribute to prevention of periodontal inflammation by decreasing gingival oxidative stress and expression of pro-inflammatory cytokines.