Poster: Bioactive Polyphenol Antioxidants Protect Oral Fibroblasts from ROS Inducing Agents

Oral tissues acquire oxidative damage from exposure to free radicals generated by lifestyle choices, the environment and some dental procedures. In this study, hydrogen peroxide (H2O2), ethanol (EtOH) and nicotine (Nic) decreased cell viability/DNA synthesis and elevated reactive oxygen species (ROS) on cultured oral fibroblasts. The oral fibroblasts were then treated with bioactive antioxidant (AO) ... Read more

Management of Bisphosphonate-Related Osteonecrosis with a Topical Antioxidant Gel

Case studies of 3 patients with Bisphosphonate-related osteonecrosis of the jaw (BRONJ) which concludes that antioxidants topically applied to areas of BRONJ represent a component of treatment that when combined with antimicrobial agents may promote healing. The treatment is non-invasive and well tolerated by patients. No deleterious side effects of the antioxidant gel were reported. ... Read more

Bioactive polyphenol antioxidants protect oral fibroblasts from ROS-inducing agents

Oxidative damage to soft oral tissues may result from exposure to the chemicals or biochemicals found in teeth-whitening products, dental restorations, tobacco, and alcohol. In this study, the antioxidant combinations of resveratrol, ferulic acid and tetrahydrocurcuminoid (RFT), phloretin, ferulic acid and resveratrol (PFR), phloretin, ferulic acid and tetrahydrocurcuminoid (PFT) protected the oral fibroblasts from the ... Read more

Salivary antioxidants and oral health in children with autism

101 subjects with autism between ages 6 and 12 year were part of this study, along with 50 normal healthy siblings of the same age group as the control group, to evaluate the oral health status of children with autism and to determine their salivary pH and total salivary antioxidant concentration (TAC.) Results: A statistically significant difference ... Read more

So Why Do We Call It the Oral-Systemic Health Connection?

Should oral health and systemic health actually be considered two different entities? We propose that the associations between oral diseases and other diseases elsewhere in the body be discussed within the context of oral and overall health, much in the same way a physician would. Even if we began using the words ‘oral’ and ‘non-oral’ ... Read more

Oral Health Behaviors, Periodontal Disease, and Pathogens in Preeclampsia: A Case-Control Study in Korea

Preeclampsia is a pregnancy-specific disease characterized by hypertension and proteinuria. This disease occurs in 3% of pregnant women in developing countries and remains one of the major causes of maternal and neonatal mortality and morbidity throughout the world The study results indicate that preeclampsia could be associated with the maternal periodontal condition and interdental cleaning. ... Read more

The Impact of Smoking Status on Antioxidant Enzyme Activity and Malondialdehyde Levels in Chronic Periodontitis

This study investigates the impact of smoking status on the systemic and local superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) activities and malondialdehyde (MDA) levels in subjects with chronic periodontitis (CP).  Within the limitation of the study, we conclude that both periodontitis and smoking lead to significant changes in MDA production and AO enzyme ... Read more

Prevalence of Oral HPV Infection in the United States, 2009-2010

Human papillomavirus (HPV) infection is the principal cause of a distinct form of oropharyngeal squamous cell carcinoma that is increasing in incidence among men in the United States. Human papillomavirus–positive oropharyngeal squamous cell carcinomas (OSCCs) are associated with sexual behavior in contrast to HPV-negative OSCCs that are associated with chronic tobacco and alcohol use. At least ... Read more