the latest research available online
Recent data have demonstrated increased lipid peroxidation (LPO) levels and oxidative stress in periodontitis.
Important to keep oral cavity pH at higher levels to prevent periodontal diseases. The results of this study seem to contribute to the understanding of the induction of periodontal diseases in the context of nitrite-dependent production of nitrogen oxides in acidic dental plaque.
The pathogenesis of periodontitis involves anaerobic oral bacteria as well as the host response to infection and several drugs have been developed which can curtail these deleterious effects. Proanthocyanidin, a novel flavanoid extracted from grape seeds, has been shown to provide a significant therapeutic effect on endotoxin (Escherichia coli) induced experimental periodontitis in rats.
The production of reactive oxygen species (ROS) is elevated in diabetes, particularly amongst those who have poor glycemic control, and it has been hypothesized that increased ROS generation in longstanding diabetes might result in oxidative damage to DNA (Wyatt et al. 2006). Excessively high levels of free radicals cause damage to cellular proteins, membrane lipids ... Read more
Mouthwash solutions are mainly used for their antiseptic properties. They currently include synthetic agents (chlorhexidine, triclosan, etc.) or essential oils (especially Listerine). Many natural extracts may also be used. These associate both antiseptic effects and direct action on host response, due to their antioxidant, immunoregulatory, analgesic, buffering, or healing properties. The development of new technologies, ... Read more
Chronic infections, including periodontal infections, may predispose to cardiovascular disease. We investigated the relationship between periodontal microbiota and hypertension.....
Epidemiological studies have implicated periodontal disease (PD) as a risk factor for the development of cardiovascular disease (CVD).
Epidemiological studies suggest that severe periodontal disease is associated with increased cardiovascular disease risk, but the mechanisms remain unknown.
Recent meta-analyses reported a weak association between periodontal disease (PD) on clinical examination and cardiovascular disease (CVD). Systemic bacterial exposure from periodontitis, which correlates poorly with the clinical examination, has been proposed as the more biologically pertinent risk factor.
Chronic inflammation from any source is associated with increased cardiovascular risk. Periodontitis is a possible trigger of chronic inflammation. We investigated the possible association between periodontitis and coronary heart disease (CHD), focusing on microbiological aspects.