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Vitamin and mineral supplements are designed to treat and prevent deficiency syndromes and promote health. Consumers frequently misuse them, as they are guided by the belief that these supplements will prevent diseases and cure symptoms. Scientific evidence demonstrates their limited usefulness in systemic disease prevention or treatment. The author reviews demonstrated benefits in select diseases.
The substances used in aesthetic procedures, such as bleaching or other whitening agents, can cause a dramatic increase in the level of free radicals in oral tissues.
The results suggest that inflammatory stress and hyperglycemia may increase the corrosion of dental endosseous titanium-based implants, but that longer, more aggressive electrochemical conditions may be necessary to fully assess these effects.
Under the conditions of this study, toothbrushing increased the elemental release from dental casting alloys.
Brushing dental casting alloys may increase their cytotoxicity in vitro, but the increase depends heavily on the alloy type and brushing condition.
Transient exposure of casting alloys to an acidic oral environment is likely to significantly increase elemental release from Ni-based alloys, but not from high-noble or noble alloys. Elemental release is important because it plays a significant role in alloy biocompatibility.
Pathways activated by GTPPs or EGCG in normal epithelial versus tumor cells create different oxidative environments, favoring either normal cell survival or tumor cell destruction. This finding may lead to applications of naturally occurring polyphenols to enhance the effectiveness of chemo/radiation therapy to promote cancer cell death while protecting normal cells.
Dysfunction of salivary glands is often associated with aging and cancer therapy. Green tea polyphenols were previously found to protect normal epithelial cells from reactive oxygen species, and to induce apoptosis in tumor cells. The current study investigated whether -(-) epigallocatechin-3-gallate (EGCG), the major green tea polyphenol, protects normal salivary gland cells from the effects of ... Read more
The cyclin-dependent kinase inhibitor p21WAF1 participates in cell growth, differentiation, and apoptosis. p21WAF1 can be induced by green tea polyphenol EGCG in several cancer cell types...
There is evidence of reduced antioxidant (AO) defense in periodontitis and pregnancy and adverse interactions between periodontitis and pregnancy.