the latest research available online
When performing dental treatments for patients with vascular disease, providers may wish to warn patients that vascular events increase in the first 4 weeks after invasive dental treatment. Treatment of periodontal disease may reduce cardiovascular risk in the longer term, but studies have suggested a link among dental procedures, acute inflammation, and endothelial dysfunction. However, ... Read more
Smoking is associated with specific structural alterations to the lipid-A-derived 3-OH fatty acid profile in saliva that are consistent with an oral microflora of reduced inflammatory potential. These findings provide much-needed mechanistic insight into the established clinical conundrum of increased infection with periodontal pathogens but reduced clinical inflammation in smokers.
Periodontal infections have been associated with a state of chronic inflammation. To ascertain whether severe periodontitis and its treatment are associated with oxidative stress, we recruited 145 cases (periodontitis) and 56 controls in a case-control study. A further pilot intervention study of 14 cases (periodontal therapy) was performed. Blood samples were taken at baseline (case-control) ... Read more
Adding green tea catechins to a dentifrice may contribute to prevention of periodontal inflammation by decreasing gingival oxidative stress and expression of pro-inflammatory cytokines.
An antioxidant is a molecule capable of inhibiting the oxidation of other molecules. Oxidation is a chemical reaction that transfers electrons from a substance to an oxidizing agent. Oxidation reactions can produce free radicals. In turn, these radicals can start chain reactions that damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates, ... Read more
Radicals (often referred to as free radicals) are atoms, molecules, or ions with unpaired electrons on an open shell configuration. Free radicals may have positive, negative or zero charge. Even though they have unpaired electrons, by convention, metals and their ions or complexes with unpaired electrons are not radicals. [1] With some exceptions, the unpaired ... Read more
NEW WEBSITE HIGHLIGHTS DENTAL AND ANTIOXIDANT RESEARCH dentalANTIOXIDANTS.com links to studies on oral and systemic health DALLAS, Texas, January 03, 2011 - Can good oral hygiene help prevent heart attack? Why do smokers run more risk of gingivitis? Does gum disease exacerbate the effects of Alzheimer's disease? A new website, dentalANTIOXIDANTS.com, provides a link to ... Read more
Consistent, well-designed, epidemiological, animal and in vitro studies directly and indirectly support the preventive polyphenol effect against oral cancer with good evidence.
Polyphenols occurring in cocoa, coffee and tea can have a role in the prevention of cariogenic processes, due to their antibacterial action. Cocoa polyphenol pentamers significantly reduce biofilm formation and acid production by Streptococcus mutans and S. sanguinis.
Polyphenolic antioxidants from dietary sources may help lower the incidence of certain cancers, cardiovascular and neurodegenerative diseases, and DNA damage and even may have antiaging properties. This review critically examines polyphenolic antioxidants, such as flavonoids, curcumene, and resveratrol in health, disease, and aging with the hope that a better understanding of the many mechanisms involved ... Read more