Gum Disease Raises Arthritis Risk

"We've known for a while that there is an association between gum disease and rheumatoid arthritis. But our new work suggests periodontal disease is causal," says study head Jerry A. Molitor, MD, PhD, associate professor in the division of rheumatology and autoimmune disease at the University of Minnesota, Minneapolis. Compared to people with mild or ... Read more

Free Radicals and Cardiovascular Diseases: An Update

Increased production of reactive oxygen species (ROS) are involved in the development and progression of cardiovascular diseases. In a number of cardiovascular disease conditions, the delicate equilibrium between free-radical generation and antioxidant defense is altered in favor of the former, thus leading to redox imbalance i.e. escalating oxidative stress and increased tissue injury. This review ... Read more

Inflammation and Factors That May Regulate Inflammatory Response

The concept of inflammation is long established. Immune responses to injury and infection are necessary; however, they cause problems when inflammatory processes are maladaptive, leading to chronic diseases. Innovative research is needed to elucidate the intricate pathways involved in chronic inflammation. Ultimatelyl, the question is how these can be used to better diagnose or treat ... Read more

Inflammation and Periodontal Diseases: A Reappraisal - Introduction to JPerio Journal Supplement

Recognition of the research advances and importance of inflammatory mechanisms in essentially all of the chronic diseases of aging, including periodontal diseases, led the American Academy of Periodontology to convene a conference on January 29 and 30, 2008 in Boston titled, "Inflammation and Periodontal Diseases: A Reappraisal." This conference brought together opinion leaders in several ... Read more

Gum disease can increase the time it takes to become pregnant

Women who are trying to become pregnant should make sure they visit their dentist and brush their teeth regularly, after preliminary research revealed that gum disease potentially can lengthen the time it takes for a woman to become pregnant by an average of an extra two months. For the first time, fertility experts have shown ... Read more

The new periodontal disease: navigate the emerging solutions

Periodontitis is an oral disease that is not limited to local tissue destruction. Escalating evidence over 20 years of research suggests there are various inflammatory pathways that link periodontitis to systemic damage. These etiological mechanisms are all metastatic in nature, and include the following:• Metastatic spread of gram negative bacteria that gain access to the ... Read more

Gum disease affects fertility

Gum disease affects fertility, and may add two-plus months to getting pregnant.   Fertility drugs may contribute towards gingivitis.  Gum disease affects men's sperm modality.

The Collagen-Binding Protein Cnm Is Required for Streptococcus mutans Adherence to and Intracellular Invasion of Human Coronary Artery Endothelial Cells

Blocking the collagen-binding protein Cnm in Streptococcus mutans may prevent patients from developing infective endocarditis or coronary atherosclerosis.  Streptococcus mutans, a predominantly hard tissue (tooth) colonizer, is considered the primary etiologic agent of dental caries, an infectious disease that affects 60 to 90% of the population worldwide.  Streptococcus mutans was the most frequently detected bacteria ... Read more