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This review focuses predominantly on the role of reactive oxygen species (ROS) and antioxidant defense systems in the pathology of periodontitis, with a view to identifying specific therapeutic targets for future host-modulating therapies.
The study findings suggest that topical application of cetylated monounsaturated fatty acid complex, 1-tetradecanol complex (1-TDC), is a potential therapeutic approach in controlling the progression of chronic periodontal disease.
The presence of the pulpal pressure may cause increasing in fluid filtration and droplet formation in simplified adhesives containing HEMA. The adhesives containing 4-META (G-Bond) may be affected by static phase separation buy by very low osmotic droplets formation and water permeability. The three-step adhesives are less affected by these problems.
Researchers conclude that shorter telomere lengths are associated with a diagnosis of periodontitis and their measures correlate with the oxidative stress and severity of disease.
Increased production of reactive oxygen species (ROS) are involved in the development and progression of cardiovascular diseases. In a number of cardiovascular disease conditions, the delicate equilibrium between free-radical generation and antioxidant defense is altered in favor of the former, thus leading to redox imbalance i.e. escalating oxidative stress and increased tissue injury. This review ... Read more
The clinically successful non-surgical periodontal therapy tended to reduce sytemic inflammation and the concentration of some circulating cytokines for patients with type 2 diabetes mellitus (T2DM.)
The concept of inflammation is long established. Immune responses to injury and infection are necessary; however, they cause problems when inflammatory processes are maladaptive, leading to chronic diseases. Innovative research is needed to elucidate the intricate pathways involved in chronic inflammation. Ultimatelyl, the question is how these can be used to better diagnose or treat ... Read more
Recognition of the research advances and importance of inflammatory mechanisms in essentially all of the chronic diseases of aging, including periodontal diseases, led the American Academy of Periodontology to convene a conference on January 29 and 30, 2008 in Boston titled, "Inflammation and Periodontal Diseases: A Reappraisal." This conference brought together opinion leaders in several ... Read more
Oxidative stress is involved in the pathogenesis of many conditions and is caused by free radicals in concentrations that overwhelm the natural scavenging mechanisms and cause pain and inflammation. This investigation sought to determine whether pain from temporomandibular disorders was associated with increased oxidative stress as measured by biomarkers in saliva and serum. Both salivary ... Read more
Women who are trying to become pregnant should make sure they visit their dentist and brush their teeth regularly, after preliminary research revealed that gum disease potentially can lengthen the time it takes for a woman to become pregnant by an average of an extra two months. For the first time, fertility experts have shown ... Read more