the latest research available online
Human papillomavirus (HPV) infection is the principal cause of a distinct form of oropharyngeal squamous cell carcinoma that is increasing in incidence among men in the United States. Human papillomavirus–positive oropharyngeal squamous cell carcinomas (OSCCs) are associated with sexual behavior in contrast to HPV-negative OSCCs that are associated with chronic tobacco and alcohol use. At least ... Read more
This review attempts to explain the immunobiological connection between periodontal diseases and type 2 diabetes mellitus, exploring the mechanisms through which periodontal infection can contribute to the low-grade general inflammation associated with diabetes (thus aggravating insulin resistance) and discussing the impact of periodontal treatment on glycemic control in people living with both diabetes and periodontal ... Read more
This study on mice marks the first documented case in microbiology of a keystone pathogen (a low-abundance species that has disproportionate influence on its environment), catalyzing the onset of an oral disease. Porphyromonas gingivalis attacks front-line immune cells in the subgingival crevice, and reprograms them to create living conditions conducive to P. gingivalis growth. As ... Read more
The oral microbial community represents the best-characterized consortium associated with the human host. There are strong correlations between the qualitative composition of the oral microbiota and clinically healthy or diseased states. The relationship between the highly characterized periopathogenic microbial community and chronic adult type periodontitis, the most common form of disease, remains to be determined.
The combined effects of multiple oral infections were significantly associated with preterm birth, conclude the authors of this study.
Stronger antioxidant status is favorable for the achievement of clinical pregnancy. In this study, scientists describe the significance of oxidative stress and total antioxidant status in ovarian follicle, blood plasma and urine in in vitro fertilization female patients and correlate the results with the outcome of ovarian follicle stimulation, clinical pregnancy rate and etiology of ... Read more
Consumption of antioxidants, retinal peroxidation, and increasing production of free radicals have been proposed as pathogenic mechanisms in human cataractogenesis. These pathogenic factors have been more strongly related to age-related and cortical cataract formation, but some authors have proposed their role in atopic dermatitis (AD) patients with cataracts. There have been theories relating anterior subcapsular cataracts formation ... Read more
A significant association was observed between tooth loss levels and carotid artery plaque prevalence.
Recent research indicated that periodontal infection may worsen systemic diseases, including pulmonary disease. Respiratory infections, such as pneumonia and the exacerbation of chronic obstructive pulmonary disease, involve the aspiration of bacteria from the oropharynx into the lower respiratory tract. Results: The comparison of study-population demographics on the basis of age, sex, education, and income showed ... Read more
The study results showed an important correlation between oxidative stress biomarkers and periodontal disease.