Section: Antioxidants & Oral Health

This is the first evidence in an animal model that the AO gel (PerioSciences) healed gingival wounds faster than Chlorhexidine.

Oral tissues acquire oxidative damage from exposure to free radicals generated by lifestyle choices, the environment and some dental procedures. In this study, hydrogen peroxide (H2O2), ethanol (EtOH) and nicotine (Nic) decreased cell viability/DNA synthesis and elevated reactive oxygen species (ROS) on cultured oral fibroblasts. The oral fibroblasts were then treated with bioactive antioxidant (AO) ... Read more

101 subjects with autism between ages 6 and 12 year were part of this study, along with 50 normal healthy siblings of the same age group as the control group, to evaluate the oral health status of children with autism and to determine their salivary pH and total salivary antioxidant concentration (TAC.) Results: A statistically significant difference ... Read more

Among dental metals, copper showed the highest cytotoxicity against human oral squamous cell carcinoma and human submandibular gland carcinoma cells, followed by palladium-alloy, gold and silver. Normal human cells (gingival fibroblast, pulp cells, periodontal ligament fibroblast) were relatively resistant to these metals. The palladium-alloy failed to induce internucleosomal DNA fragmentation, a biochemical hallmark of apoptosis, ... Read more

Oxidative stress is involved in the pathogenesis of many conditions and is caused by free radicals in concentrations that overwhelm the natural scavenging mechanisms and cause pain and inflammation. This investigation sought to determine whether pain from temporomandibular disorders was associated with increased oxidative stress as measured by biomarkers in saliva and serum. Both salivary ... Read more

This in vitro study evaluates the antioxidant substances present in the human diet with an antimutagenic productive capacity against genotoxic damage induced by exposure to X-rays in an attempt to reduce biological damage to as low a level as reasonably possible.

There is increasing attention to the potential benefit from the use of antioxidants in the field of dental medicine. In general, antioxidants may be available through oral ingestion, diet or vitamin supplements, and in nutraceuticals. In addition, treatment of oral and dental health problems may include drug-free, natural antioxidant remedies that are available in topical ... Read more

Recent years have shown the presence of free radicals in causation and progression of various dental diseases and antioxidant usage in dental therapeutics. Antioxidant micronutrients are important not only for limiting oxidative and tissue damage, but also in preventing increased cytokine production, which is a result of prolonged activation of the immune response. There has ... Read more

Adding green tea catechins to a dentifrice may contribute to prevention of periodontal inflammation by decreasing gingival oxidative stress and expression of pro-inflammatory cytokines.