The purpose of dentalANTIOXIDANTS.com is to provide background information and current research regarding antioxidants on oral tissues. Specific areas of interest on the site include the relationships between oral and systemic health, between infection and chronic inflammatory disease, and between cardiovascular disease and inflammation, as well as the specific connection between periodontal disease and cardiovascular disease. The site will also feature research in biochemistry regarding the sources and uses of antioxidants, their reactivity with other organic compounds, and their effects on organic systems including oral cells.

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The objective of the site is to identify and evaluate as much of the emerging research as possible and make it available on this site. Scientists and scholars at Baylor College of Dentistry are involved in the massive project of reviewing all the possibly-relevant research. In addition, distinguished practitioners and researchers in various disciplines of dentistry, medicine, and biochemistry will be invited to participate as members of the Professional Review Board, reviewing research studies as well as contributing their own opinions and evaluations.

Because of the breadth and depth of information on the emerging science of antioxidants in dentistry and systemic health, dentalANTIOXIDANTS.com presents a uniquely valuable source for professional education. Work is under way to develop academic courses that will offer continuing education (CE) units accepted by dental hygiene and dental technician accreditation institutions. The courses, which will be deliverable in both online format as well as live lecture series, promise to be user-friendly, stimulating and practical.

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Kathy Svoboda Kathy K. H. Svoboda, PhD is a Regents Professor of Biomedical Sciences and Graduate Program Director at Baylor College of Dentistry which is part of the Texas A&M University Health Science Center. In addition, Dr. Svoboda is an Adjunct Professor of Ophthalmology at Southwestern Medical School in Dallas, TX. She has a Masters of Science degree in Human Genetics and a Ph.D. in Anatomy from the University of Nebraska Medical Center located in Omaha, Nebraska. In addition, she was a Research Fellow in the Department of Anatomy and Cellular Biology at Harvard Medical School. She has held faculty positions at Harvard Medical School, Boston University School of Medicine and Baylor College of Dentistry. Dr. Svoboda has been a member of several NIH study sections including the NIH and NSF Shared Instrument Study Sections and NIH VISA and AED Study Sections. Dr. Svoboda is a Past President and Fellow of the American Association of Anatomists and a Silver Fellow in the Association for Research in Vision and Ophthalmology. Show more

Dr. Svoboda has a broad background in developmental and cell biology, with specific training and expertise in signal transduction. As the principle investigator on several previous university and PerioSciences funded grants, she designed experiments to determine effective antioxidant combinations that counteract the effects of oral stressors (nicotine, ethanol, H2O2, dental materials) in a variety of cell based and animal assays. Her research has been supported by NIH, NSF, March of Dimes, PerioSciences and the Baylor Oral Health Foundation.

Dr. Svoboda has mentored over 40 postdoctoral, PhD, MS graduate students, undergraduate, medical and dental predoctoral students, and college/high school summer research trainees. Her students have obtained many travel and student competition awards including:� five finalists, one 3rd place and two 2nd place winners in the American Association of Anatomists Jan Langman competition; one Balint Orban honorable mention; two Hatton finalist; one Henry Russek Student Award. Student grants include: NIH F30 Research Fellow, KO8 and F32 NRSA, American Association of University Women Education Foundation Dissertation Award, and Graduate Student Research Award from Boston Univ. School of Medicine. Show less

Review Board


Edwared Allen Edward Allen, DDS, PhD received his DDS from Baylor College of Dentistry in 1969. He completed a Residency in Periodontics and earned a PhD in Physiology from Baylor University Graduate School. Dr. Allen is Adjunct Professor in the Department of Periodontics at Baylor College of Dentistry and is in full-time private practice in Dallas, Texas.

Dr. Allen has served as President of the American Academy of Esthetic Dentistry, the American Academy of Restorative Dentistry and the American Academy of Periodontology Foundation. Show more

He currently serves as the Periodontal Section Editor for the Journal of Esthetic Dentistry and serves on the Editorial Boards of the Journal of Periodontology and the International Journal of Periodontics and Restorative Dentistry.

Dr. Allen received the Distinguished Alumnus Award from the Baylor College of Dentistry Periodontics Residency Program, the Master Clinician Award from the American Academy of Periodontology and the President’s Award from the American Academy of Esthetic Dentistry for Excellence in Dental Education. Dr. Allen is Founder and Director of the Center for Advanced Dental Education in Dallas, Texas where he teaches surgical technique courses. He has published over 50 articles in the area of esthetic surgery and continues to present numerous lectures and surgical demonstrations worldwide. Show less
Bruce Bowers Bruce Bowers, MD, FACC is an interventional cardiologist with The Dallas Heart Group with affiliations with THE HEART HOSPITAL Baylor Plano, Baylor Regional Medical Center in Plano and Medical City Dallas Hospital in Dallas, Texas. He is Co-Director, Vascular Clinical Research Division and Principal Investigator, Peripheral Vascular Clinical Trials at THE HEART HOSPITAL Baylor Regional Medical Center. In addition, he is a Co-Investigator for the PARTNER trial (Transcatheter Aortic Valve Replacement) at Medical City Dallas Hospital. Show more

Dr. Bowers has an extensive background in peripheral vascular disease with clinical interests in: coronary intervention and coronary vascular disease, transcatheter aortic valve replacement, PFO closure, ASD closure, endovascular repair of AAA, carotid artery angioplasty and stenting, brachiocephalic, renal, iliac, remoral, and infrapopliteal intervention. He also has accredited noninvasive credentials in Echocardiography and Nuclear Cardiology.

Dr. Bowers received his Bachelor of Arts degree with a major in Neuroscience from Wesleyan University in 1993 and was awarded a Medical Doctorate degree in 1998 from Saint George’s University School of Medicine, Grenada, West Indies. His clinical clerkships were completed at New York Presbyterian Hospital and Robert Wood Johnson University School of Medicine Hospital Affiliates in New York, New York and Short Hills, New Jersey. He finished his Internal Medicine internship and residency training program in 2001 at the Medical College of Pennsylvania – Hahnemann University Hospital, Department of Internal Medicine. In 2004, he completed his Cardiovascular Medicine fellowship training program at the Medical College of Pennsylvania – Hahnemann University Hospital, Department of Cardiovascular Medicine. Dr. Bowers went on to complete a peripheral and coronary interventional training program in 2005 at Medical College of Pennsylvania – Hahnemann University Hospital, Department of Interventional Cardiology.

Dr. Bowers is a Fellow of the American College of Cardiology and holds professional memberships in the Society of Angiography and Intervention and the American Medical Association. In addition, he was the recipient of the Outstanding Fellow Award from Hahnemann University Hospital in 2003-2004. Dr. Bowers has been named to the prestigious "Best Doctors in America" list for 2010-2011. This is an honor bestowed on the top 5% of physicians in the country. Show less
Karen Davis Karen Davis, RDH, BSDH received her Bachelor of Science in Dental Hygiene from Midwestern State University. She is founder of Cutting Edge Concepts® an International continuing education company. Karen has over 30 years experience in clinical in dental hygiene, and currently merges lecturing with private practice. Karen is also a trainer with The JP Institute, and has served on numerous advisory boards in the profession. She has been recognized as one of the ‘Leaders in Continuing Education’ in Dentistry Today for several years.
Casey Hein Casey Hein, BSDH, MBA is an Assistant Clinical Professor in the Department of Periodontics, and Director of Education of the International Centre for Oral-Systemic Health, in the Faculty of Dentistry, and an Assistant Professor in the Office of Continued Professional Development, and Director of Interprofessional Development, in the Faculty of Medicine, University of Manitoba. In these positions, she is developing the first comprehensive, multi-media curriculum specifically related to oral-systemic relationships for non-dental healthcare providers such as physicians, nurses, pharmacists, dieticians, among others; and translating evidence of oral-systemic relationships into models of interprofessional collaboration. Casey also has a dental education company, Casey Hein & Associates, LLC. Show more

She holds a Bachelor of Science degree in Dental Hygiene from West Virginia University and Masters of Business Administration from Loyola. Casey has over 30 years of experience as a dental hygienist in private practice, education, public health, and consulting. With over 100 published articles and international lectures, she is best recognized for her work in clinical integration of well supported evidence of periodontal-systemic relationships in dentistry, medicine, and allied healthcare. She serves on the advisory boards of several companies and as an independent consultant to the dental industry.

Casey founded the first journal on this subject, Grand Rounds in Oral-Systemic Medicine and was the principal originator of “The Scottsdale Project” and lead author on The Report of the Independent Panel of Experts of the Scottsdale Project. This was the first time that expert academicians and researchers from medicine and dentistry were brought together to determine whether there is sufficient evidence of a relationship between periodontal disease and diabetes and cardiovascular disease to recommend that guidelines be developed for the medical-dental co-management of these interrelated diseases.

Casey is a member of the American Dental Hygienists’ Association, Colorado Dental Hygienists’ Association, American Association of Diabetes Educators, American Dental Education Association, National Speakers Association, and the Speakers and Consultants Network. She has been voted among the Top 100 Clinicians in Continuing Education by Dentistry Today for the last 6 consecutive years. Show less

Harold Heymann Harald O. Heymann, DDS, MEd graduated from the University of North Carolina School of Dentistry. He is the past Chairman and Graduate Program Director of the Department of Operative Dentistry and currently is Professor of Operative Dentistry at the UNC School of Dentistry.

Dr. Heymann is particularly active in the clinical research of esthetic restorative materials and participates in a dental practice devoted largely to esthetic dentistry. Show more
He is a member of Academy of Operative Dentistry, the International Association of Dental Research, and is Past-President and a Fellow of the American Academy of Esthetic Dentistry. He is also a Fellow in the International College of Dentists, the American College of Dentists, and the Academy of Dental Materials. He also serves as a consultant to the ADA.

The author of over 185 scientific publications, Dr. Heymann also has authored a number of textbook chapters on conservative esthetic techniques and is Co-Editor of The Art and Science of Operative Dentistry. Dr. Heymann is also the Editor-in-Chief of the Journal of Esthetic and Restorative Dentistry. Dr. Heymann has given over 1,200 lectures on various aspects of esthetic dentistry worldwide, is a Board Member of the CRA Foundation, and has received the Gordon J. Christensen Award for excellence as a CE speaker. Show less
John Kois John C. Kois, DMD, MSD received his DMD from the University of Pennsylvania, School of Dental Medicine and Certificate in Periodontal Prosthodontics with a MSD degree from the University of Washington, School of Dentistry. He maintains a private practice limited to Prosthodontics in Tacoma and Seattle and is an Affiliate Professor in the Graduate Restorative Program at the University of Washington. Dr. Kois continues to lecture nationally and internationally, is a reviewer for many journals and is the Editor in Chief for The Compendium of Continuing Education in Dentistry. Show more

Dr. Kois is the recipient of the 2002 Saul Schluger Memorial Award for Clinical Excellence in Diagnosis and Treatment Planning, and received a Lifetime Achievement Award from both the World Congress of Minimally Invasive Dentistry and the American Academy of Cosmetic Dentistry. He is the past President of both the American Academy of Restorative Dentistry and American Academy of Esthetic Dentistry, and a member of numerous other professional organizations. In addition, he continues to work with restorative dentists at the Kois Center, a didactic and clinical teaching program. Show less
Samuel Low Samuel B. Low, DDS, MS, MEd, Professor Emeritus, University of Florida, College of Dentistry; Associate faculty member of the Pankey with 30 years of private practice experience in periodontics and implant placement. He is also a Diplomate of the American Board of Periodontology and President of the American Academy of Periodontology. Dr. Low provides dentists and dental hygienists with the tools for successfully managing the periodontal patient in general and periodontal practices and is affiliated with the Florida Probe Corporation. He was selected “Dentist of the Year” by the Florida Dental Association, Distinguished Alumnus by the University of Texas Dental School, and the Gordon Christensen Lecturer Recognition Award. He is a Past President of the Florida Dental Association and presently 17th district ADA Trustee.
Salavador Nares Salvador Nares, DDS, PhD is an Assistant Professor in the Department of Periodontology at the University of North Carolina at Chapel Hill, School of Dentistry. He received his DDS, PhD, and Certificate of Specialty in Periodontology from Baylor College of Dentistry (Texas A&M) in Dallas, Texas. Dr. Nares completed a 3 year post-doctoral fellowship at the Oral Infection and Immunity Branch of the National Institute of Dental and Craniofacial Research, National Institutes of Health in Bethesda, Maryland where he focused on the role of antigen-presenting cells (monocytes, macrophages, dendritic cells) in the inflammatory response to periodontal pathogens. At UNC, his primary research focus is on the regulation of periodontal and peri-dental implant inflammation and wound healing. His research has been supported by NIH, UNC, and the American Academy of Implant Dentistry among others. Show more

Dr. Nares is the Graduate Program Director in the Department of Periodontology at UNC. In addition to clinical mentoring, he also serves as scientific mentor for numerous residents, post-doctoral fellows, dental and pre-dental students. Dr. Nares serves on peer review panels of numerous dental and scientific journals and serves regionally and nationally on educational performance committees. He is a Diplomate of the American Academy of Periodontology and maintains a clinical practice limited to Periodontology and Implantology. Show less
Trisha E. O'Hehir Trisha E. O'Hehir, RDH, MS graduated from the University of Minnesota and her four decade career in dental hygiene has included clinical positions in the USA and Zurich, Switzerland; faculty positions at the Universities of Minnesota, Washington, Arizona and Louisville; international speaking; writing; and instrument designing. Currently she is the Editorial Director of Hygienetown Magazine/online community and Editor of Perio Reports. Trisha has published over 300 feature articles bridging the gap between published research and clinical practice. Show more

Her volunteer work includes a position on the Board of Directors of AD Word Health, a foundation bringing medical and dental care to children in orphanages worldwide. Among her numerous awards are the Distinguished Alumni Award from the University of Minnesota, and the Warner-Lambert/ADHA Excellence in Dental Hygiene Award. Trisha currently resides in Arizona, where she is a Past-President of the Arizona State Dental Hygienists' Association. As an international speaker, she presents thought provoking programs combining current research, practical applications, and alternatives for the future. Show less
Rebecca Wilder Rebecca S. Wilder, RDH, MS is a Professor and Director of Faculty Development for the University of North Carolina at Chapel Hill School of Dentistry. She also serves as Director of the Master of Science Degree Program in Dental Hygiene Education and she is the Interim Director of the undergraduate dental hygiene programs. She taught periodontology to dental hygiene students for 10 years and currently teaches management/administration and thesis / research design. She is former co-director of the practice management course for junior dental students and Advanced Education General Dentistry residents. Show more

Professor Wilder is currently the Editor-in-Chief of the Journal of Dental Hygiene through the American Dental Hygienists’ Association. She is also an editor for the Second Edition of Mosby’s Dental Hygiene: Concepts, Cases, Competencies. She has served as chair of the ADHA Institute for Oral Health Research Grant Review Committee, the ADHA Council on Research and President of the Oral Health Research Group of the International Association of Dental Research. Professor Wilder is a former recipient of the Colgate/IADR Oral Health Research Award for outstanding accomplishments in oral health research and also the Pfizer/ADHA Award for Excellence in Dental Hygiene. In 2007, she received the Alumni Achievement Award from the University of Missouri -Kansas City. In 2007-08, she was an ADEA Leadership Institute Fellow though the American Dental Education Association. She has published over 100 articles and abstracts in professional journals and she is an international speaker in the areas of periodontics, oral-systemic health, risk and practice management. Show less

Featured Content

Article in Press - Archives of Oral Biology (2011)
Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts

Antioxidants (AO) are the first line of defence against free radical damage and are critical for maintaining optimum health and well being. The need for AOs becomes even more critical with increased...

Journal of Dental Research November 2010 vol. 89 no. 11 1241-1246
Oxidative Stress, Systemic Inflammation, and Severe Periodontitis

Periodontal infections have been associated with a state of chronic inflammation. To ascertain whether severe periodontitis and its treatment are associated with oxidative stress, we recruited 145 cases (periodontitis) and 56 controls...

Journal of Periodontology 2010 Nov;81(11):1675-90
Antioxidants Counteract Nicotine and Promote Migration via RacGTP in Oral Fibroblast Cells

Smoking is associated with an increased risk of oral health and dental problems, and may impair wound healing by increasing reactive oxygen species (ROS) and inhibiting cell migration. Treatment with antioxidant (AO)...

Journal of Dental Research January 2011 vol. 90 no. 1 47-52
Fatty Acid Profiles in Smokers with Chronic Periodontitis

Smoking is associated with specific structural alterations to the lipid-A-derived 3-OH fatty acid profile in saliva that are consistent with an oral microflora of reduced inflammatory potential. These findings provide much-needed mechanistic...

Journal of Dentistry 2009 Dec;37(12):932-6
Reaction kinetics of sodium ascorbate and dental bleaching gel.

The aim of this study was to establish the reaction kinetics of 35% hydrogen peroxide and sodium ascorbate and to determine the mass of antioxidant required to neutralize the bleaching gel. The...

Journal of Dentistry 2009 Jun;37(6):413-23.
Polyphenols, oral health and disease: A review.

Consistent, well-designed, epidemiological, animal and in vitro studies directly and indirectly support the preventive polyphenol effect against oral cancer with good evidence.